Misuses of models overstates significance

A brief comment points out a major flaw in a published study, in part by using simulations:

Our reanalysis illustrates two important points. First, studies of complex trait genetics require very large sample sizes to be well powered, and a study reporting a highly significant association from such a small sample size should elicit skepticism. Second, unnecessarily complex statistical methods can obscure rather than reveal the truth. The simplest analysis is sometimes the best.